Cosmelan Depigmenting Professional Treatment

Cosmelan is a professional depigmenting method that fully removes the most severe and resistant spots with maximum efficacy and safety. The cosmelan method is a unique combination of active ingredients of proven efficacy that provides it with a unique and dual action for a short- and long-term outcome:

  • Corrective action: visibly removes and attenuates spots.
  • Regulating action: it regulates the overproduction of pigmentation to prevent the spots' reappearance.

Included in the set:

Cosmelan 2 | 1 oz

  • Depigmenting cream. Home treatment supplementing cosmelan 1 that reduces spots continuously and regulates melanin overproduction to prevent their reappearance.

Oil Removing Solution | 0.34 oz

  • Enhances penetration of active ingredients, maximising the efficacy of treatment.

Cosmelan 1 

  • Professional treatment with a concentrated formula that allows to stimulate intensively skin renewal to remove the existing spots. 

Melan Recovery Cream | 1.69 oz

  • Soothing, recovery balm. Relieves the treatment’s characteristic feeling of tightness and reduces sensitivity, inflammation and redness.

Melan 130 Pigment Control SPF | 1.69 oz

  • Specific anti-spot photoprotection. Very high sun screen (131 UVB and 67 UVA) with colour that helps control skin pigmentation.

Mesoestetic is a medical-grade skincare line with highly active and effective ingredients. We offer virtual complimentary consultations if you would like further assistance finding a product tailored to your needs.


Mesoestetic only sells certain products through licensed medical professionals. We have licensed in-house estheticians ready to call you for a free 5 minute consultation.

Prep- mesoestetic® hydra milk cleanser backbar

1. Cleanse the skin with mesoestetic® hydra milk cleanser backbar using

circular motions, and remove cleanser with warm water using facial sponges

2. Degrease the skin with mesoestetic® oil removing solution using gauze

3. Protect the mucus membranes on the face (tear ducts, nostrils, and lips) using

a mesolips protector.

Method - mesoestetic® cosmelan® 1 mask

4. With a spatula dispense ¾ of mesoestetic® cosmelan® 1 mask and apply an

even thick layer on entire face. Avoid the eye contour area.

5. Determine time on tissue according to professional recommendation. (Refer to

time on tissue chart)

6. Patient goes home with recommended masked application protocol.


1. Consultation plays a huge role, professional must educate patient on

treatment protocol and home care protocol.

2. It is recommended to use at least ¾ of the jar for the initial mask application.

Save ¼ for “spot treatment” which should be done 21 days after initial mask


3. During application time and after removing the mask, the patient must avoid

exposure to sources of light and heat.

4. Spritz water on face to prevent mask from cracking, without removing the


5. For Asian skin types, it is recommended not to leave the mask on longer than

5 hours. These are recommended application times only.

6. Consideration should be taken in accordance to skin sensitivity, evolution of

pigment, and professional expertise with the product. 

7. Different degrees of peeling vary per patient and the integrity of the skin.

8. Provide patient with detailed home care maintenance protocol.

9. Results may vary from patient to patient.

10. Mild to moderate erythema, stinging sensation, and tightening of the

skin are to be expected after 24 to 48 hours of the cosmelan® 1 mask


11. If excess stinging sensation occurs while applying cosmelan® 2 cream, this

may be adjusted.

12. After the time indicated by the professional, the patient should carefully

rinse cosmelan® 1 mask out with plenty of tepid water. Repeat as often as

required to remove the product completely.

13. See the cosmelan2® home care protocol for more detailed home care


oil removing solution

ingredients: acetone, alcohol, aqua, citic acid, ci 42090.

cosmelan 1

ingredients: aqua, caprylic/capric triglyceride, azelaic acid, titanium dioxide, aloe barbadensis leaf juice, copernicia cerifera cera, kojic acid, peg-8 beeswax, glycerin, glyceryl stearate, ethoxydiglycol, alpha-arbutin, cetearyl alcohol, niacinamide, phytic acid, poloxamer 407, sodium ascorbyl phosphate, ceteareth-25, bisabolol, magnesium aluminium silicate, stearyl dimethicone, tocopheryl acetate, retinyl palmitate, behenyl alcohol, disodium

ethylene dicocamide peg-15 disulfate, xanthan gum, sodium lauroyl lactylate, ascorbic acid, citric acid, salicylic acid, allantoin, acacia senegal gum,

glyceryl stearate citrate, sodium metabisulfite, phenoxyethanol, tocopherol.

cosmelan 2

ingredients: aqua, caprylic/capric triglyceride, azelaic acid, aloe barbadensis leaf juice, sodium ascorbyl phosphate, titanium dioxide, glycerin, kojic acid, poloxamer 407, glyceryl stearate, ethoxydiglycol, hydroxypropyl starch phosphate, alpha-arbutin, butylene glycol dicaprylate/dicaprate,

cyclomethicone, ethylhexyl methoxycinnamate, niacinamide, di-c12-13 alkyl malate, ceteareth-25, peg-8 beeswax, stearic acid, tocopheryl acetate, retinyl palmitate, dimethicone, alcohol, behenyl alcohol, disodium ethylene dicocamide peg-15 disulfate, citric acid, ascorbic acid, bisabolol, salicylic acid, sclerotium gum, sorbitan stearate, stearyl dimethicone, sodium lauroyl lactylate, aminoeethylphosphinic acid, rumex occidentalis extract, acacia senegal gum, glyceryl stearate citrate, glycyrrhiza glabra root extract, allantoin, sodium metabisulfite, butylene glycol, phytic acid, xanthan gum, phenoxyethanol, manganese oxide, tocopherol.

melan recovery

ingredients: aqua, butyrospermum parkii butter, caprylic/capric triglyceride, glycerin, isodecyl neopentanoate, pentylene glycol, stearyl alcohol,

squalane, candelilla/jojoba/rice bran polyglyceryl-3 esters, glyceryl stearate, 1,2-hexanediol, dimethicone, cetearyl alcohol, bisabolol, cetyl alcohol, ectoin, inulin, yogurt powder, rhodosorus marinus extract, niacinamide, sodium stearoyl lactylate, xanthan gum, propanediol, disodium edta, parfum.

mesoprotech® melan 130

ingredients: aqua, dibutyl adipate, octocrylene, cyclopentasiloxane, homosalate, bis-ethylhexyloxyphenyl triazyne, alcohol, butyl methoxydibenzoylmethane, titanium dioxide, methylene bis-benzotriazolyl tetramethylbutylphenol, cyclohexasiloxane, peg-30 dipolyhydroxystearate, polysilicone-15, styrene/acrylates copolymer, peg-10 dimethicone, silica, bis-ethylhexyl hydroxydimethoxy benzylmalonate, polyamide-5, potassium azeloyl diglycinate, jojoba esters, hexyl laurate, helianthus annuus seed oil, dimethicone, ethylhexylglycerine, acacia decurrens flower wax, polyglycerin-3, polyamide-3, cetyl peg/ppg-10/1 dimethicone, polyglyceryl-4 isostearate, sodium chloride, vp/hexadecene copolymer, decyl glucoside, disteardimonium hectorite, disodium edta, peg-12 allyl ether, hydrogenated lecithin, propylene glycol, xanthan gum, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, phenoxyethanol, parfum, ci 77492, ci 77491,

ci 77499.